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Vol 3, Number 4, Jul 2009

Number 4, July 2009

Editorials

Editorial: Given the complexity of the human genome, can ‘personalized medicine’ or ‘individualized drug therapy’ ever be achieved?
Daniel W. Nebert, University Cincinnati Medical Center

Guest Editorial: Collection of variation causing disease: The Human Variome Project
Richard G.H. Cotton, Human Variome Project, Howard Florey Institute and Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne

Research Papers:

Identification of a novel cytosolic aldehyde dehydrogenase allele, ALDH1A1*4
Shelley M. Moore, Department of Paraclinical Sciences, Faculty of Medical Sciences, University of the West Indies et al.
 
Recommendations for using standardized phenotypes in genetic association studies
Melissa G. Naylor, Christoph Lange, Department of Biostatistics, Harvard University and Scott T. Weiss, Channing Laboratory, Brigham and Women’s Hospital

Review Papers:

The tiny world of MicroRNAs in the cross hairs of the mammalian eye
Robert M. Lavker, Jia-Yu and David G Ryan, Departments of Dermatology and Ophthalmology, Northwestern University

Human genomic diversity, viral genomics and proteomics, as exemplified by Human Papillomaviruses and H5N1 Influenza Viruses
Meena K. Sakharkar, Kishore R. Sakharkar, Biomedical Engineering Research Centre, Nanyang Technological University and Vincent T.K. Chow, Yong Loo Lin School of Medicine, National University of Singapore

Genome Update:

Aldo-keto reductase (AKR) superfamily: Genomics and annotation
Rebekka D. Mindnich and Trevor M. Penning, Center for Excellence in Environmental Toxicology, Department of Pharmacology, University of Pennsylvania

Software Review:

Current software for genotype imputation
David Ellinghaus, Stefan Schreiber, Andre Franke, Institute of Clinical Molecular Biology and Michael Nothnagel, Institute of Medical Informatics and Statistics, Christian-Albrechts University

Book Review:

Animal Models in Eye Research Edited by Panagiotis A. Tsonis
Reviewed by Michael L. Robinson, Assistant Professor, Zoology, Miami University